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ING2 抗体 (AA 112-141)

This anti-ING2 antibody is a 兔 多克隆 antibody detecting ING2 in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881460
发货至: 中国

Quick Overview for ING2 抗体 (AA 112-141) (ABIN1881460)

抗原

See all ING2 抗体
ING2 (Inhibitor of Growth Family, Member 2 (ING2))

适用

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宿主

  • 23
  • 6
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克隆类型

  • 25
  • 5
多克隆

标记

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This ING2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40520
  • 抗原表位

    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 112-141

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ING2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-141 amino acids from the Central region of human ING2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ythier, Larrieu, Binet, Binda, Brambilla, Gazzeri, Pedeux: "Sumoylation of ING2 regulates the transcription mediated by Sin3A." in: Oncogene, Vol. 29, Issue 44, pp. 5946-56, (2010) (PubMed).

    Larrieu, Ythier, Binet, Brambilla, Brambilla, Sengupta, Pedeux: "ING2 controls the progression of DNA replication forks to maintain genome stability." in: EMBO reports, Vol. 10, Issue 10, pp. 1168-74, (2009) (PubMed).

    Kumamoto, Fujita, Kurotani, Saito, Unoki, Hagiwara, Shiga, Bowman, Yanaihara, Okamura, Nagashima, Miyamoto, Takenoshita, Yokota, Harris: "ING2 is upregulated in colon cancer and increases invasion by enhanced MMP13 expression." in: International journal of cancer. Journal international du cancer, Vol. 125, Issue 6, pp. 1306-15, (2009) (PubMed).

    Borkosky, Gunduz, Nagatsuka, Beder, Gunduz, Ali, Rodriguez, Cilek, Tominaga, Yamanaka, Shimizu, Nagai: "Frequent deletion of ING2 locus at 4q35.1 associates with advanced tumor stage in head and neck squamous cell carcinoma." in: Journal of cancer research and clinical oncology, Vol. 135, Issue 5, pp. 703-13, (2009) (PubMed).

    Unoki, Kumamoto, Robles, Shen, Zheng, Harris: "A novel ING2 isoform, ING2b, synergizes with ING2a to prevent cell cycle arrest and apoptosis." in: FEBS letters, Vol. 582, Issue 28, pp. 3868-74, (2008) (PubMed).

  • 抗原

    ING2 (Inhibitor of Growth Family, Member 2 (ING2))

    别名

    ING2

    背景

    This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.

    分子量

    32808

    NCBI登录号

    NP_001555

    UniProt

    Q9H160

    途径

    Chromatin Binding, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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