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Granulin 抗体 (C-Term)

Cited in 3+ publications. This 兔 多克隆 anti-Granulin antibody (Clone RB44397) specifically detects Granulin in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN1881391
发货至: 中国
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Quick Overview for Granulin 抗体 (C-Term) (ABIN1881391)

抗原

See all Granulin (GRN) 抗体
Granulin (GRN)

适用

  • 62
  • 10
  • 4
  • 1
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  • 1

宿主

  • 52
  • 10
  • 5
  • 2
  • 1
  • 1

克隆类型

  • 49
  • 22
多克隆

标记

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  • 1
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This Granulin antibody is un-conjugated

应用范围

  • 62
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  • 6
  • 3
  • 3
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB44397
  • 抗原表位

    • 15
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
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    AA 563-591, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the C-terminal region of human GRN.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Bhandari, Bateman: "Structure and chromosomal location of the human granulin gene." in: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 57-63, (1992) (PubMed).

    Plowman, Green, Neubauer, Buckley, McDonald, Todaro, Shoyab: "The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth." in: The Journal of biological chemistry, Vol. 267, Issue 18, pp. 13073-8, (1992) (PubMed).

    Bhandari, Palfree, Bateman: "Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 5, pp. 1715-9, (1992) (PubMed).

  • 抗原

    Granulin (GRN)

    别名

    GRN

    背景

    Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.

    分子量

    63544

    NCBI登录号

    NP_002078

    UniProt

    P28799
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