Granulin 抗体 (C-Term)
Quick Overview for Granulin 抗体 (C-Term) (ABIN1881391)
抗原
See all Granulin (GRN) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 563-591, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GRN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-591 amino acids from the C-terminal region of human GRN.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Structure and chromosomal location of the human granulin gene." in: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 57-63, (1992) (PubMed).
: "The epithelin precursor encodes two proteins with opposing activities on epithelial cell growth." in: The Journal of biological chemistry, Vol. 267, Issue 18, pp. 13073-8, (1992) (PubMed).
: "Isolation and sequence of the granulin precursor cDNA from human bone marrow reveals tandem cysteine-rich granulin domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 5, pp. 1715-9, (1992) (PubMed).
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: "Structure and chromosomal location of the human granulin gene." in: Biochemical and biophysical research communications, Vol. 188, Issue 1, pp. 57-63, (1992) (PubMed).
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- Granulin (GRN)
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别名
- GRN
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背景
- Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
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分子量
- 63544
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NCBI登录号
- NP_002078
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UniProt
- P28799
抗原
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