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Estrogen Receptor alpha 抗体 (C-Term)

Name: Estrogen Receptor alpha 抗体 (C-Term)
SKU: ABIN1881317
Availability: OutOfStock

This anti-Estrogen Receptor alpha antibody is a 兔多克隆 antibody detecting Estrogen Receptor alpha in WB 和 IF. Suitable for 人. This Primary Antibody has been cited in 3+ publications.

Western blot analysis of ESR1 isoform1 Antibody (C-term) Pab (ABIN1881317 and ABIN2838677) pre-incubated without(lane 1) and with(lane 2) blocking peptide in K562 cell line lysate. (Estrogen Receptor alpha 抗体 (C-Term))

Fluorescent confocal image of MCF-7 cell stained with ESR1 isoform1 Antibody (C-term) (ABIN1881317 and ABIN2838677). (Estrogen Receptor alpha 抗体 (C-Term))

2 images

(3 references)

产品编号 ABIN1881317

发货至: 中国

Quick Overview for Estrogen Receptor alpha 抗体 (C-Term) (ABIN1881317)

抗原

See all Estrogen Receptor alpha (ESR1) 抗体

Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

适用

人

宿主

兔

克隆类型

多克隆

标记

This Estrogen Receptor alpha antibody is un-conjugated

应用范围

Western Blotting (WB), Immunofluorescence (IF)

克隆位点

RB41149

Discover our top product ESR1 Primary Antibody

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AA 452-480, C-Term

预测反应

Hs, M, Pig, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ESR1 isoform1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the C-terminal region of human ESR1 isoform1.

亚型

Ig Fraction
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibody
ESR1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal ESR1-3557 unconjugated

anti-Estrogen Receptor 1 (ESR1) antibody
ESR1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ESR1-1904 unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibody
ESR1 适用: 人, 大鼠 WB, IHC, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6A6E8 unconjugated

anti-Estrogen Receptor 1 (ESR1) (pSer167) antibody
ESR1 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibody
ESR1 适用: 人 WB, IHC, FACS, StM 宿主: 小鼠 Monoclonal ER506 unconjugated

anti-Estrogen Receptor 1 (ESR1) (C-Term) antibody
ESR1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibody
ESR1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB33807 unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibody
ESR1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (AA 331-360) antibody
ESR1 适用: 人, 大鼠 WB, ELISA, FACS, IF (cc) 宿主: 兔 Polyclonal unconjugated

anti-Estrogen Receptor 1 (ESR1) (pSer118) antibody
ESR1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Geradts, Bean, Bentley, Barry: "The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features." in: Cancer investigation, Vol. 28, Issue 9, pp. 969-77, (2010) (PubMed).

Hayes, Skaar, Rae, Henry, Nguyen, Stearns, Li, Philips, Desta, Flockhart: "Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results." in: Clinical pharmacology and therapeutics, Vol. 88, Issue 5, pp. 626-9, (2010) (PubMed).

Lupien, Meyer, Bailey, Eeckhoute, Cook, Westerling, Zhang, Carroll, Rhodes, Liu, Brown: "Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance." in: Genes & development, Vol. 24, Issue 19, pp. 2219-27, (2010) (PubMed).
抗原

Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

别名

ESR1

背景

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

分子量

66216

NCBI登录号

NP_000116, NP_001116212, NP_001116213, NP_001116214

UniProt

P03372

途径

Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly