电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ErbB2/Her2 抗体 (pSer1051)

This anti-ErbB2/Her2 antibody is a 兔 多克隆 antibody detecting ErbB2/Her2 in DB. Suitable for 小鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881306
发货至: 中国

Quick Overview for ErbB2/Her2 抗体 (pSer1051) (ABIN1881306)

抗原

See all ErbB2/Her2 抗体
ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

适用

  • 536
  • 130
  • 121
  • 33
  • 8
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 300
  • 251
  • 10
  • 6
  • 3
  • 2
  • 2
  • 1

克隆类型

  • 294
  • 276
  • 3
多克隆

标记

  • 318
  • 33
  • 21
  • 14
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 1
This ErbB2/Her2 antibody is un-conjugated

应用范围

  • 314
  • 205
  • 141
  • 129
  • 114
  • 93
  • 84
  • 80
  • 72
  • 60
  • 53
  • 46
  • 29
  • 12
  • 9
  • 8
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dot Blot (DB)

克隆位点

RB41772
  • 抗原表位

    • 87
    • 32
    • 30
    • 30
    • 25
    • 25
    • 24
    • 17
    • 17
    • 15
    • 13
    • 13
    • 10
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    pSer1051

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This mouse ERBB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1051 of mouse ERBB2.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Cabodi, Tinnirello, Bisaro, Tornillo, del Pilar Camacho-Leal, Forni, Cojoca, Iezzi, Amici, Montani, Eva, Di Stefano, Muthuswamy, Tarone, Turco, Defilippi: "p130Cas is an essential transducer element in ErbB2 transformation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3796-808, (2010) (PubMed).

    Johnson, Seachrist, DeLeon-Rodriguez, Lozada, Miedler, Abdul-Karim, Keri: "HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29491-501, (2010) (PubMed).

    Huck, Pontier, Zuo, Muller: "beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 35, pp. 15559-64, (2010) (PubMed).

    Chuang, Chen, Lin, Veeramani, Kumar, Batra, Tu, Lin: "Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23598-606, (2010) (PubMed).

    Simeone, Straubinger, Khan, Nalleweg, Cheusova, Hashemolhosseini: "Identification of Erbin interlinking MuSK and ErbB2 and its impact on acetylcholine receptor aggregation at the neuromuscular junction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 19, pp. 6620-34, (2010) (PubMed).

  • 抗原

    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

    别名

    ERBB2

    背景

    Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity).

    分子量

    138579

    NCBI登录号

    NP_001003817

    UniProt

    P70424

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
You are here:
Chat with us!