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ErbB2/Her2 抗体 (pSer1051)

ErbB2/Her2 适用: 小鼠 DB 宿主: 兔 Polyclonal RB41772 unconjugated
产品编号 ABIN1881306
发货至: 中国
  • 抗原 See all ErbB2/Her2 抗体
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    抗原表位
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    pSer1051
    适用
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    小鼠
    宿主
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    克隆类型
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    多克隆
    标记
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    This ErbB2/Her2 antibody is un-conjugated
    应用范围
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    Dot Blot (DB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This mouse ERBB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1051 of mouse ERBB2.
    克隆位点
    RB41772
    亚型
    Ig Fraction
    Top Product
    Discover our top product ErbB2/Her2 Primary Antibody
  • 应用备注
    DB: 1:500
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Cabodi, Tinnirello, Bisaro, Tornillo, del Pilar Camacho-Leal, Forni, Cojoca, Iezzi, Amici, Montani, Eva, Di Stefano, Muthuswamy, Tarone, Turco, Defilippi: "p130Cas is an essential transducer element in ErbB2 transformation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3796-808, (2010) (PubMed).

    Johnson, Seachrist, DeLeon-Rodriguez, Lozada, Miedler, Abdul-Karim, Keri: "HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29491-501, (2010) (PubMed).

    Huck, Pontier, Zuo, Muller: "beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 35, pp. 15559-64, (2010) (PubMed).

    Chuang, Chen, Lin, Veeramani, Kumar, Batra, Tu, Lin: "Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23598-606, (2010) (PubMed).

    Simeone, Straubinger, Khan, Nalleweg, Cheusova, Hashemolhosseini: "Identification of Erbin interlinking MuSK and ErbB2 and its impact on acetylcholine receptor aggregation at the neuromuscular junction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 19, pp. 6620-34, (2010) (PubMed).

  • 抗原
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    别名
    ERBB2 (ErbB2/Her2 产品)
    背景
    Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity).
    分子量
    138579
    NCBI登录号
    NP_001003817
    UniProt
    P70424
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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