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EIF3E 抗体 (AA 248-276)

Name: EIF3E 抗体 (AA 248-276)
SKU: ABIN1881290
Availability: OutOfStock

This anti-EIF3E antibody is a 兔多克隆 antibody detecting EIF3E in WB. Suitable for 人和斑马鱼. This Primary Antibody has been cited in 5+ publications.

EIF3E Antibody (Center) (ABIN1881290 and ABIN2838389) western blot analysis in K562 cell line lysates (35 μg/lane). (EIF3E 抗体 (AA 248-276))

(DANRE) eif3eb Antibody (Center) (ABIN1881290 and ABIN2838389) western blot analysis in zebra fish brain tissue lysates (35 μg/lane). (EIF3E 抗体 (AA 248-276))

2 images

(5 references)

产品编号 ABIN1881290

发货至: 中国

Quick Overview for EIF3E 抗体 (AA 248-276) (ABIN1881290)

抗原

See all EIF3E 抗体

EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))

适用

人, 斑马鱼

宿主

兔

克隆类型

多克隆

标记

This EIF3E antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB40515

Discover our top product EIF3E Primary Antibody

抗原表位
6

4

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 248-276

预测反应

X, B, C, Pr, M, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This EIF3E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-276 amino acids from the Central region of human EIF3E.

亚型

Ig Fraction
anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (Middle Region) antibody
EIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 346-445) antibody
EIF3E 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 1-445) antibody
EIF3E 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 36-85) antibody
EIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (N-Term) antibody
EIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (C-Term) antibody
Verified EIF3E 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 360-409) antibody
EIF3E 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 豚鼠, 马, 兔, 猴, Pig, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (AA 1-445) antibody
EIF3E 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) antibody
EIF3E 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E) (C-Term) antibody
EIF3E 适用: 人, 小鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000. WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Grzmil, Rzymski, Milani, Harris, Capper, Saunders, Salhan, Ragoussis, Norbury: "An oncogenic role of eIF3e/INT6 in human breast cancer." in: Oncogene, Vol. 29, Issue 28, pp. 4080-9, (2010) (PubMed).

Zhou, Sandercock, Fraser, Ridlova, Stephens, Schenauer, Yokoi-Fong, Barsky, Leary, Hershey, Doudna, Robinson: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, (2008) (PubMed).

Morris, Wittmann, Jäck, Jalinot: "Human INT6/eIF3e is required for nonsense-mediated mRNA decay." in: EMBO reports, Vol. 8, Issue 6, pp. 596-602, (2007) (PubMed).

Masutani, Sonenberg, Yokoyama, Imataka: "Reconstitution reveals the functional core of mammalian eIF3." in: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, (2007) (PubMed).

Sirchia, Luparello: "Mid-region parathyroid hormone-related protein (PTHrP) and gene expression of MDA-MB231 breast cancer cells." in: Biological chemistry, Vol. 388, Issue 5, pp. 457-65, (2007) (PubMed).
抗原

EIF3E (Eukaryotic Translation Initiation Factor 3 Subunit E (EIF3E))

别名

EIF3E

背景

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Required for nonsense-mediated mRNA decay (NMD), may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.

分子量

52221

NCBI登录号

NP_001559

UniProt

P60228

途径

Ribonucleoprotein Complex Subunit Organization, Hepatitis C