CLDN14 抗体 (C-Term)
(3 references)Quick Overview for CLDN14 抗体 (C-Term) (ABIN1881208)
抗原
See all CLDN14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 172-200, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CLDN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 172-200 amino acids from the C-terminal region of human CLDN14.
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亚型
- Ig Fraction
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anti-Claudin 14 (CLDN14) (AA 140-239) antibody
CLDN14 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 14 (CLDN14) (C-Term) antibodyVerified CLDN14 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Claudin 14 (CLDN14) (AA 1-239) antibodyCLDN14 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Claudin 14 (CLDN14) (AA 29-81) antibodyCLDN14 适用: 人 ELISA, IP 宿主: 小鼠 Monoclonal 3D11 unconjugated
anti-Claudin 14 (CLDN14) (C-Term) antibodyCLDN14 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 14 (CLDN14) (AA 29-81) antibodyCLDN14 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Claudin 14 (CLDN14) (AA 177-239) antibodyCLDN14 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 14 (CLDN14) (C-Term) antibodyCLDN14 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density." in: Nature genetics, Vol. 41, Issue 8, pp. 926-30, (2009) (PubMed).
: "Mutation in gap and tight junctions in patients with non-syndromic hearing loss." in: Biochemical and biophysical research communications, Vol. 385, Issue 1, pp. 1-5, (2009) (PubMed).
: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).
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: "Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density." in: Nature genetics, Vol. 41, Issue 8, pp. 926-30, (2009) (PubMed).
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- CLDN14 (Claudin 14 (CLDN14))
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别名
- CLDN14
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背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects in this gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reported that four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
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分子量
- 25699
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NCBI登录号
- NP_001139549, NP_001139550, NP_001139551, NP_036262, NP_652763
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UniProt
- O95500
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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