Cyclin D2 抗体 (C-Term)
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Quick Overview for Cyclin D2 抗体 (C-Term) (ABIN1881177)
抗原
See all Cyclin D2 (CCND2) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 258-285, C-Term
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预测反应
- B, Pig
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CCND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-285 amino acids from the C-terminal region of human CCND2.
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亚型
- Ig Fraction
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anti-Cyclin D2 (CCND2) (AA 161-288) antibody
CCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 47-267) antibodyCCND2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 68-278) antibodyCCND2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 1-289) antibodyCCND2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (AA 215-285) antibodyCCND2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (C-Term) antibodyCCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin D2 (CCND2) (pThr280) antibodyCCND2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- Cyclin D2 (CCND2)
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别名
- CCND2
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背景
- Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D2/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
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分子量
- 33067
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NCBI登录号
- NP_001750
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UniProt
- P30279
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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