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Cyclin B3 抗体 (pThr280)

There are 3+ publications for this product available. The 兔 多克隆 anti-Cyclin B3 antibody is suitable to detect Cyclin B3 in samples from 人. It has been validated for DB.
产品编号 ABIN1881173
发货至: 中国
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Quick Overview for Cyclin B3 抗体 (pThr280) (ABIN1881173)

抗原

See all Cyclin B3 (CCNB3) 抗体
Cyclin B3 (CCNB3)

适用

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宿主

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克隆类型

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多克隆

标记

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This Cyclin B3 antibody is un-conjugated

应用范围

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Dot Blot (DB)

克隆位点

RB42155
  • 抗原表位

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    pThr280

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CCNB3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T280 of human CCNB3.

    亚型

    Ig Fraction
  • 应用备注

    DB: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Cheng, Kapranov, Drenkow, Dike, Brubaker, Patel, Long, Stern, Tammana, Helt, Sementchenko, Piccolboni, Bekiranov, Bailey, Ganesh, Ghosh, Bell, Gerhard, Gingeras: "Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution." in: Science (New York, N.Y.), Vol. 308, Issue 5725, pp. 1149-54, (2005) (PubMed).

    Mouland, Coady, Yao, Cohen: "Hypophosphorylation of poly(A) polymerase and increased polyadenylation activity are associated with human immunodeficiency virus type 1 Vpr expression." in: Virology, Vol. 292, Issue 2, pp. 321-30, (2002) (PubMed).

    Nguyen, Manova, Capodieci, Lindon, Bottega, Wang, Refik-Rogers, Pines, Wolgemuth, Koff: "Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin." in: The Journal of biological chemistry, Vol. 277, Issue 44, pp. 41960-9, (2002) (PubMed).

  • 抗原

    Cyclin B3 (CCNB3)

    别名

    CCNB3

    背景

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chick and Drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and be required for proper spindle reorganization and restoration of the interphase nucleus. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    157916

    NCBI登录号

    NP_149020, NP_391990

    UniProt

    Q8WWL7

    途径

    Cell Division Cycle, Chromatin Binding
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