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CBS 抗体 (N-Term)

This anti-CBS antibody is a 兔 多克隆 antibody detecting CBS in WB, IF, IHC (p) 和 FACS. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1881141
发货至: 中国

Quick Overview for CBS 抗体 (N-Term) (ABIN1881141)

抗原

See all CBS 抗体
CBS (Cystathionine-beta-Synthase (CBS))

适用

  • 60
  • 47
  • 15
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 72
  • 11

克隆类型

  • 65
  • 18
多克隆

标记

  • 48
  • 6
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CBS antibody is un-conjugated

应用范围

  • 65
  • 34
  • 25
  • 18
  • 13
  • 13
  • 12
  • 11
  • 8
  • 7
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

克隆位点

RB22961
  • 抗原表位

    • 15
    • 9
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 104-133, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CBS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the N-terminal region of human CBS.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

    Lee, Mariappan, Feliers, Cavaglieri, Sataranatarajan, Abboud, Choudhury, Kasinath: "Hydrogen sulfide inhibits high glucose-induced matrix protein synthesis by activating AMP-activated protein kinase in renal epithelial cells." in: The Journal of biological chemistry, Vol. 287, Issue 7, pp. 4451-61, (2012) (PubMed).

  • 抗原

    CBS (Cystathionine-beta-Synthase (CBS))

    别名

    CBS

    背景

    CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

    分子量

    60587

    NCBI登录号

    NP_000062, NP_001171479, NP_001171480

    UniProt

    P35520
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