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CNR1 抗体 (AA 161-187)

Cited in 4+ publications. This 兔 多克隆 anti-CNR1 antibody (Clone RB41743) specifically detects CNR1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881140
发货至: 中国
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Quick Overview for CNR1 抗体 (AA 161-187) (ABIN1881140)

抗原

See all CNR1 抗体
CNR1 (Cannabinoid Receptor 1 (CNR1))

适用

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宿主

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克隆类型

  • 78
  • 24
多克隆

标记

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This CNR1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41743
  • 抗原表位

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    AA 161-187

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-187 amino acids of human CB1.

    亚型

    IgG
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Van Laere, Casteels, Dhollander, Goffin, Grachev, Bormans, Vandenberghe: "Widespread decrease of type 1 cannabinoid receptor availability in Huntington disease in vivo." in: Journal of nuclear medicine : official publication, Society of Nuclear Medicine, Vol. 51, Issue 9, pp. 1413-7, (2010) (PubMed).

    Monteleone, Milano, Petrella, Canestrelli, Maj: "Endocannabinoid Pro129Thr FAAH functional polymorphism but not 1359G/A CNR1 polymorphism is associated with antipsychotic-induced weight gain." in: Journal of clinical psychopharmacology, Vol. 30, Issue 4, pp. 441-5, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Larrinaga, Varona, Pérez, Sanz, Ugalde, Cándenas, Pinto, Gil, López: "Expression of cannabinoid receptors in human kidney." in: Histology and histopathology, Vol. 25, Issue 9, pp. 1133-8, (2010) (PubMed).

  • 抗原

    CNR1 (Cannabinoid Receptor 1 (CNR1))

    别名

    CB1

    背景

    This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq].

    分子量

    52858

    NCBI登录号

    NP_001153698, NP_001153730, NP_001153731, NP_057167, NP_149421

    UniProt

    P21554

    途径

    Feeding Behaviour
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