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CASQ2 抗体 (AA 79-107)

This anti-CASQ2 antibody is a 兔 多克隆 antibody detecting CASQ2 in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1881138
发货至: 中国

Quick Overview for CASQ2 抗体 (AA 79-107) (ABIN1881138)

抗原

See all CASQ2 抗体
CASQ2 (Calsequestrin 2 (CASQ2))

适用

  • 32
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1

宿主

  • 30
  • 5

克隆类型

  • 31
  • 4
多克隆

标记

  • 20
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CASQ2 antibody is un-conjugated

应用范围

  • 24
  • 17
  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB41817
  • 抗原表位

    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 79-107

    预测反应

    Rb

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Kirchhefer, Wehrmeister, Postma, Pohlentz, Mormann, Kucerova, Müller, Schmitz, Schulze-Bahr, Wilde, Neumann: "The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling." in: Journal of molecular and cellular cardiology, Vol. 49, Issue 1, pp. 95-105, (2010) (PubMed).

    Wei, Hanna, Beard, Dulhunty: "Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle." in: Cell calcium, Vol. 45, Issue 5, pp. 474-84, (2009) (PubMed).

  • 抗原

    CASQ2 (Calsequestrin 2 (CASQ2))

    别名

    CASQ2

    背景

    The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].

    分子量

    46436

    NCBI登录号

    NP_001223

    UniProt

    O14958

    途径

    Negative Regulation of Transporter Activity
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