CASQ2 抗体 (AA 79-107)
Quick Overview for CASQ2 抗体 (AA 79-107) (ABIN1881138)
抗原
See all CASQ2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 79-107
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预测反应
- Rb
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CASQ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the Central region of human CASQ2.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling." in: Journal of molecular and cellular cardiology, Vol. 49, Issue 1, pp. 95-105, (2010) (PubMed).
: "Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle." in: Cell calcium, Vol. 45, Issue 5, pp. 474-84, (2009) (PubMed).
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: "The human CASQ2 mutation K206N is associated with hyperglycosylation and altered cellular calcium handling." in: Journal of molecular and cellular cardiology, Vol. 49, Issue 1, pp. 95-105, (2010) (PubMed).
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- CASQ2 (Calsequestrin 2 (CASQ2))
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别名
- CASQ2
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背景
- The protein encoded by this gene specifies the cardiac muscle family member of the calsequestrin family. Calsequestrin is localized to the sarcoplasmic reticulum in cardiac and slow skeletal muscle cells. The protein is a calcium binding protein that stores calcium for muscle function. Mutations in this gene cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest. [provided by RefSeq].
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分子量
- 46436
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NCBI登录号
- NP_001223
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UniProt
- O14958
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途径
- Negative Regulation of Transporter Activity
抗原
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