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S1PR5 抗体 (C-Term)

The 兔 多克隆 anti-S1PR5 antibody is suitable to detect S1PR5 in samples from 人. It has been validated for WB.
产品编号 ABIN187790
发货至: 中国
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Quick Overview for S1PR5 抗体 (C-Term) (ABIN187790)

抗原

See all S1PR5 抗体
S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

适用

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宿主

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克隆类型

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多克隆

标记

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This S1PR5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    Reacts with EDG-8. Species Reactivity: Human, other species not tested.

    过滤

    Sterile filtered

    免疫原

    Synthetic peptide derived from the C-terminus of the human EDG-8 protein.
  • 应用备注

    Western Blot: Use at 5-10 µg/mL using a human EDG-8 receptor transfected cell line. Detects recombinant EDG-8 receptors with a band of about 42 kDa. [ Note: Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for Western blot development.] The optimal dilution for a specific application should be determined by the researcher.

    限制

    仅限研究用
  • 缓冲液

    Purified sterile filtered polyclonal antibody against human EDG-8 (CT). 100 µg/100 µL in PBS with 0.08% sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

    别名

    EDG-8 / S1P5

    背景

    Endothelial Cell Differentiation Gene-8 (EDG-8) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-8 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-8 is expressed in oligodendrocytes and fibrous astrocytes in the rat brain.
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