TLR3 抗体
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北京 101111
Quick Overview for TLR3 抗体 (ABIN187555)
抗原
See all TLR3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human Toll-like Receptor 3 (TLR3). Species Reactivity: Human and mouse. Others not tested.
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免疫原
- Synthetic peptides derived from the cytoplasmic portion of human TLR3.
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亚型
- IgG1
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anti-Toll-Like Receptor 3 (TLR3) (AA 404-532) antibody
TLR3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 464-647) antibodyTLR3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 801-905) antibodyTLR3 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 24-217) antibodyTLR3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 6F3G4 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 135-297) antibodyTLR3 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 55-70) antibodyTLR3 适用: 人, 猴, 山羊, 绵羊 WB, IHC, IP, FACS, IHC (p) 宿主: 小鼠 Monoclonal 40C1285-6 unconjugated
anti-Toll-Like Receptor 3 (TLR3) antibodyTLR3 适用: 小鼠 FACS, IF 宿主: 大鼠 Monoclonal 11F8 unconjugated
anti-Toll-Like Receptor 3 (TLR3) (C-Term) antibodyTLR3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 3 (TLR3) (AA 750-800), (pTyr759) antibodyTLR3 适用: 人 WB, IHC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: Use 2-5 µg/106 cells for intracellular staining. Immunoprecipitation: Use 2 µg/106 transfected cells. Western blot: Use at 1-3 µg/mL. Immunohistochemistry: (paraffin sections) Immunocytochemistry The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 µg of liquid Protein G purified monoclonal antibody at 0.5 mg/mL in PBS containing protein stabilizer and 0.05% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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别名
- CD283 / TLR3
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背景
- The Toll-like receptor (TLR) family in mammals comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin-1 receptor-associated kinase (IRAK) signaling pathway. Ten human homologs of TLRs (TLR1-10) have been described. TLR3 cDNA codes for a protein, ~120 kDa. TLR3 has a restricted expression pattern being expressed in dendritic cells (DC). TLR3 mRNA expression was detected by in situ hybridization in DC and lymph nodes. The expression of TLR3 in a single cell type may indicate a specific role for this molecule in a restricted setting.
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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