Clusterin 抗体
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北京 101111
Quick Overview for Clusterin 抗体 (ABIN187541)
抗原
See all Clusterin (CLU) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human clusterin. Species Reactivity: Human. Others not tested.
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纯度
- 95 % as determined by SDS-PAGE.
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免疫原
- Purified human clusterin (TRPM-2).
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亚型
- IgG1
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应用备注
- Immunohistochemistry: Frozen sections. Immunoprecipitation Immunocytochemistry Western blot: Use at approximately a 1:2,000 dilution. The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 µg of liquid purified monoclonal antibody at 1 mg/mL in PBS containing 0.02% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- Clusterin (CLU)
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别名
- Apolipoprotein J (Clusterin)
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背景
- Clusterin is the first identified extracellular mammalian chaperone and appears to be implicated in such diverse processes as sperm maturation, regulation of complement activation, programmed cell death, tissue remodeling and lipid transport. Increases in clusterin mRNA and protein have been consistently detected in apoptotic cell death paradigms, establishing clusterin gene expression as a prominent marker of apoptotic cell loss. A dual role has been shown for clusterin in that cells can be protected from damage and dead cells can be more easily removed after some types of cellular damage.
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途径
- Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
抗原
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