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TRAIL 抗体

TNFSF10 适用: 人 WB, FACS, IP, EIA, IHC (fro) 宿主: 小鼠 Monoclonal IIIF6 unconjugated
产品编号 ABIN187524
发货至: 中国
  • 抗原 See all TRAIL (TNFSF10) 抗体
    TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
    适用
    • 101
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    宿主
    • 79
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    小鼠
    克隆类型
    • 82
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    单克隆
    标记
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    This TRAIL antibody is un-conjugated
    应用范围
    • 90
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    Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Recognizes human TRAIL Species Reactivity: Human.
    免疫原
    Recombinant human soluble TRAIL (Apo-2L)
    克隆位点
    IIIF6
    亚型
    IgG2b
    Top Product
    Discover our top product TNFSF10 Primary Antibody
  • 应用备注
    Western blotting Flow Cytometry Immunohistochemistry: Frozen sections Immunoprecipitation ELISA The optimal dilution for a specific application should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    100 µl of purified antibody in PBS containing 0.02% NaN3. Concentration 1 mg/ml IgG.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
    别名
    CD253 / TRAIL (TNFSF10 产品)
    别名
    APO2L antibody, Apo-2L antibody, CD253 antibody, TL2 antibody, TRAIL antibody, A330042I21Rik antibody, AI448571 antibody, APO-2L antibody, Ly81 antibody, Trail antibody, tl2 antibody, apo2l antibody, cd253 antibody, trail antibody, apo-2l antibody, trail1 antibody, xtrail1 antibody, tnfsf10l2 antibody, zgc:92320 antibody, TNLG6A antibody, TNF superfamily member 10 antibody, tumor necrosis factor (ligand) superfamily, member 10 antibody, tumor necrosis factor superfamily member 10 antibody, TNF superfamily member 10 S homeolog antibody, TNFSF10 antibody, Tnfsf10 antibody, tnfsf10.S antibody, tnfsf10 antibody
    背景
    Tumor necrosis factor (TNF-)-related apoptosis-inducing ligand (TRAIL, APO-2L) is thought to regulate cell death events in the immune system through TRAIL-R1 (DR4) and TRAIL-R2 (DR5), members of the TNF receptor superfamily. Like the death receptors, including Fas and TNF-R, TRAIL-R1 and TRAIL-R2 have death domains in their cytoplasmic tails that recruit proteins to initiate a cell death signaling cascade. TRAIL (APO-2L) is a 34 kDa type II transmembrane protein. TRAIL forms trimers and is a member of the TNF ligand family. Interaction between TRAIL and TRAIL-R1 and/or TRAIL-R2 rapidly induces apoptosis of TRAIL-sensitive cells. TRAIL can be injected into mice without toxic side effects. Many tumor cells are killed by TRAIL and TRAIL is currently being considered as on of the most promising potential new cancer therapeutics.
    途径
    Apoptosis, Positive Regulation of Endopeptidase Activity
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