Caspase 7 抗体 (N-Term)
Quick Overview for Caspase 7 抗体 (N-Term) (ABIN187518)
抗原
See all Caspase 7 (CASP7) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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过滤
- 0.2 μm filtered
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免疫原
- Synthetic peptide corresponding to amino acids 1 to 11 of the human caspase-7 enzyme.
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亚型
- IgG1
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anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-303) antibody
CASP7 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 207-303) antibodyCASP7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 29-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4D10B2 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 24-198) antibodyCASP7 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) antibodyCASP7 适用: 人, 小鼠, 大鼠, 猴, Pig, 犬, 兔, Hamster, 绵羊 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 7-1-11 unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) antibodyCASP7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 1-250) antibodyCASP7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (AA 1-303) antibodyCASP7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7) (N-Term) antibodyCASP7 适用: 人, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western Blot The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Mouse monoclonal antibody against human Caspase-7 (cysteine-requiring aspartate protease-7). Available in 100 ul vials at a concentration of 1 mg/ml (100ug) in PBS with 0.08% sodium azide. The antibody is 0.2 um sterile filtered.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))
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别名
- Caspase-7
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背景
- Caspases are key effectors of programmed cell death. Caspase-7 along with caspase 3 and 6 form the group of effector caspases that are responsible for the cleavage of multiple substrates including the cytokeratins, PARP, alpha lodrin, NuMa and others. Caspase-7 is a 303 amino acid protein with high similarity to caspase-3. Caspase-7 is found in three variant forms. Granzyme B activates pro-caspase-7 to a form which can cleave PARP to its key fragment of about 85 kDa. Also, in vivo caspase-7 appears to be a better substrate for granzyme B than caspase-3. Pro-caspase-7 has been shown to exist as dimers or high order oligomers. Caspase-7 may be an important intracellular effector of granzyme B-medicated apoptosis and cytotoxic T-lymphocyte-induced cell killing in vivo.
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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