BAFF 抗体
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北京 101111
Quick Overview for BAFF 抗体 (ABIN187404)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes the stalk region present in the membrane-bound form of human BAFF. Species Reactivity: Human, others not tested.
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免疫原
- Human sol. BAFF (rec., aa. 83-285)
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亚型
- IgG2a
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应用备注
- Flow Cytometry: optimal concentration range is 0.5-5 µg/ml. Western blotting The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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浓度
- 1 mg/ml. Purity > 95% as determined by SDS-PAGE. The antibody was purified from concentrated hybridoma cell culture supernatant.
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缓冲液
- 100 µg in PBS and 0.02% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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别名
- CD257 / BAFF
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背景
- BAFF (for B-cell activating factor belonging to the TNF family), a new member of the tumor necrosis factor (TNF) family was simultaneously identified by four different laboratories and named BAFF, TALL-1, THANK, zTNF4. It is abundantly expressed in monocytes and macrophages, upregulated by interferon gamma. Endogenous BAFF is processed intracellularly by a protease of the furin family of proprotein convertases. Secreted BAFF acts as a potent B cell growth factor. Recently, two receptors for BAFF have been identified and termed as BCMA and TACI.
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
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