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BAFF 抗体

TNFSF13B 适用: 人 WB, FACS 宿主: 大鼠 Monoclonal Buffy-1 unconjugated
产品编号 ABIN187404
发货至: 中国
  • 抗原 See all BAFF (TNFSF13B) 抗体
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    适用
    • 120
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    宿主
    • 79
    • 40
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    • 1
    大鼠
    克隆类型
    • 90
    • 53
    单克隆
    标记
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    This BAFF antibody is un-conjugated
    应用范围
    • 78
    • 59
    • 48
    • 32
    • 15
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    Western Blotting (WB), Flow Cytometry (FACS)
    特异性
    Recognizes the stalk region present in the membrane-bound form of human BAFF. Species Reactivity: Human, others not tested.
    免疫原
    Human sol. BAFF (rec., aa. 83-285)
    克隆位点
    Buffy-1
    亚型
    IgG2a
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    Discover our top product TNFSF13B Primary Antibody
  • 应用备注
    Flow Cytometry: optimal concentration range is 0.5-5 µg/ml. Western blotting The optimal dilution for a specific application should be determined by the researcher.
    限制
    仅限研究用
  • 浓度
    1 mg/ml. Purity > 95% as determined by SDS-PAGE. The antibody was purified from concentrated hybridoma cell culture supernatant.
    缓冲液
    100 µg in PBS and 0.02% sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
    别名
    CD257 / BAFF (TNFSF13B 产品)
    背景
    BAFF (for B-cell activating factor belonging to the TNF family), a new member of the tumor necrosis factor (TNF) family was simultaneously identified by four different laboratories and named BAFF, TALL-1, THANK, zTNF4. It is abundantly expressed in monocytes and macrophages, upregulated by interferon gamma. Endogenous BAFF is processed intracellularly by a protease of the furin family of proprotein convertases. Secreted BAFF acts as a potent B cell growth factor. Recently, two receptors for BAFF have been identified and termed as BCMA and TACI.
    途径
    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
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