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Myeloperoxidase 抗体

MPO 适用: 人, 大鼠 FACS, IHC (fro) 宿主: 小鼠 Monoclonal 8F4 unconjugated
产品编号 ABIN187335
发货至: 中国
  • 抗原 See all Myeloperoxidase (MPO) 抗体
    Myeloperoxidase (MPO)
    适用
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    人, 大鼠
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Myeloperoxidase antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Monoclonal antibody 8F4 reacts with MPO. Species Reactivity: Human and rat. Others not tested.
    过滤
    0.2 μm filtered
    克隆位点
    8F4
    亚型
    IgG1
    Top Product
    Discover our top product MPO Primary Antibody
  • 应用备注
    Flow Cytometry: The typical starting dilution is 1:10. Immunohistochemistry: (Frozen sections)-The typical starting dilution is 1:10. The optimal dilution for a specific application should be determined by the researcher.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    1 ml containing 100 µg IgG in PBS with 0.1% BSA. The antibody solution was filtered through a 0.2 micron filter.
    储存条件
    4 °C
  • 抗原
    Myeloperoxidase (MPO)
    别名
    Myeloperoxidase (MPO 产品)
    别名
    mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody
    背景
    Myeloperoxidase (MPO) is a glycoprotein with an alpha2beta2 heteromultimer expressed in all cells of the myeloid lineage. MPO is abundantly present in azurophilic granules of polymorphonuclear neutrophils. It is an important enzyme used during phagocytic lysis of engulfed foreign particles which takes part in the defense of the organism through production of hypochlorous acid (HOCl), a potent oxidant. MPO is rapidly released by activated polymorphonuclear neutrophils. Involvement of MPO has been described in numerous diseases such as atherosclerosis, lung cancer, Alzheimer's disease and multiple sclerosis. Autoimmune antibodies to MPO are involved in Wegeners disease. Since the discovery of MPO deficiency, initially regarded as rare and restricted to patients suffering from severe infections, MPO has attracted more clinical attention. In experimental studies antibodies to MPO can be used for various purposes ranging from flow cytometric analysis to detection of polymorphonuclear neutrophils in tissue sections.
    途径
    Chromatin Binding
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