KPNA3 抗体 (C-Term)
(3 references)Quick Overview for KPNA3 抗体 (C-Term) (ABIN185159)
抗原
See all KPNA3 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- KPNA3 / IPOA4
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序列
- DPTANLQTKE FNF
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交叉反应
- Cow, 犬, 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-DPTANLQTKEFNF, from the C Terminus of the protein sequence according to NP_002258.2.
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亚型
- IgG
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anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (AA 1-210) antibody
KPNA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibodyKPNA3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (AA 3-220) antibodyKPNA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (AA 422-521) antibodyKPNA3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibody (Biotin)Verified KPNA3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IP, IF, ICC 宿主: 山羊 Polyclonal Biotin
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (N-Term) antibodyKPNA3 适用: 人, 小鼠, 大鼠, 豚鼠, 斑马鱼, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Karyopherin alpha 3 (Importin alpha 4) (KPNA3) (C-Term) antibodyKPNA3 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry: Paraffin embedded Human Testis. Recommended concentration: 6 μg/mL.
Western Blot: Approx. 60 kDa band observed in lysates of cell lines CaCo-2, HEK293 and MCF7 (calculated MW of 57.8 kDa according to NP_002258.2). Recommended concentration: 0.01-0.03 μg/mL. Primary incubation 1 hour at room temperature.
Peptide ELISA: antibody detection limit dilution 1:128000.
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说明
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Immunofluorescence: Strong expression of the protein seen in the cytoplasm and nuclei of A431 cells. Recommended concentration: 10μg/ml.
Flow Cytometry: Flow cytometric analysis of A431 cells. Recommended concentration
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1226-9, (2015) (PubMed).
: "Axotomy induces axonogenesis in hippocampal neurons by a mechanism dependent on importin ?." in: Biochemical and biophysical research communications, Vol. 405, Issue 4, pp. 697-702, (2011) (PubMed).
: "Notch1 signaling is mediated by importins alpha 3, 4, and 7." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 18, pp. 3187-96, (2010) (PubMed).
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: "Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS." in: Nature neuroscience, Vol. 18, Issue 9, pp. 1226-9, (2015) (PubMed).
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- KPNA3 (Karyopherin alpha 3 (Importin alpha 4) (KPNA3))
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别名
- KPNA3
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背景
- KPNA3, IPOA4, karyopherin alpha 3 (importin alpha 4), RP11-432M24.3, SRP1gamma, SRP4, hSRP1, importin alpha 4, importin alpha 4, importin-alpha-Q2, karyopherin alpha 3, SRP1, importin alpha-3
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基因ID
- 3839, 16648
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NCBI登录号
- NP_002258
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途径
- Protein targeting to Nucleus
抗原
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