FOXA2 抗体 (C-Term)
Quick Overview for FOXA2 抗体 (C-Term) (ABIN185022)
抗原
See all FOXA2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- FOXA2 / HNF3B
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序列
- GVYSRPIMNS S
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特异性
- This antibody is expected to recognise both reported isoforms: NP_068556.2, NP_710141.1
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence C-GVYSRPIMNSS, from the C Terminus of the protein sequence according to NP_068556.2, NP_710141.1.
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亚型
- IgG
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应用备注
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Immunohistochemistry: In paraffin embedded Human Prostate shows nuclear staining in the secretory cells of the gland. Recommended concentration: 4-8 μg/mL.
Western Blot: Approx 60 kDa band observed in Human Liver and Rat Lung lysates (calculated MW of 48.3 kDa according to Human NP_710141.1 and 48.5 kDa according to Rat NP_036875.1). The observed molecular weight corresponds to earlier findings in literature (
Peptide ELISA: antibody detection limit dilution 1:4000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9768-76, (2007) (PubMed).
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: "Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver." in: The Journal of biological chemistry, Vol. 282, Issue 13, pp. 9768-76, (2007) (PubMed).
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- FOXA2 (Forkhead Box A2 (FOXA2))
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别名
- FOXA2
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背景
- FOXA2, HNF3B, forkhead box A2, TCF3B, MGC19807, hepatic nuclear factor-3-beta, hepatocyte nuclear factor 3, beta
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基因ID
- 3170, 15376, 25099
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NCBI登录号
- NP_068556, NP_710141
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途径
- Dopaminergic Neurogenesis, Regulation of Carbohydrate Metabolic Process
抗原
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