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ALDH2 抗体 (AA 317-517)

This anti-ALDH2 antibody is a 小鼠 单克隆 antibody detecting ALDH2 in WB, IHC, ELISA, FACS 和 IF/ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1846467
发货至: 中国

Quick Overview for ALDH2 抗体 (AA 317-517) (ABIN1846467)

抗原

See all ALDH2 抗体
ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

适用

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人, 小鼠, 大鼠

宿主

  • 62
  • 17
  • 2
小鼠

克隆类型

  • 58
  • 23
单克隆

标记

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This ALDH2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)
  • 抗原表位

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    • 1
    AA 317-517

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human ALDH2 (AA: 317-517) expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

    别名

    ALDH2

    背景

    This protein belongs to the aldehyde dehydrogenase family of proteins.Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism.Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations.Most Caucasians have two major isozymes, while approximately 50% of Orientals have the cytosolic isozyme but not the mitochondrial isozyme.A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme.The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer.This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix.Alternative splicing results in multiple transcript variants encoding distinct isoforms.

    分子量

    56.3 kDa

    基因ID

    217
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