CCL2 抗体
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北京 101111
Quick Overview for CCL2 抗体 (ABIN1846382)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human CCL2 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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别名
- CCL2
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背景
- This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4.
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分子量
- 11 kDa
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基因ID
- 6347
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UniProt
- P13500
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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