WHSC2 抗体 (AA 280-511)
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北京 101111
Quick Overview for WHSC2 抗体 (AA 280-511) (ABIN1846367)
抗原
See all WHSC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 280-511
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human WHSC2 (AA: 280-511) expressed in E. coli.
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亚型
- IgG2b
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
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别名
- WHSC2
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背景
- This gene is expressed ubiquitously with higher levels in fetal than in adult tissues.It encodes a protein sharing 93% sequence identity with the mouse protein.Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4.This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome.The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients.This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
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分子量
- 57.3 kDa
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基因ID
- 7469
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途径
- Chromatin Binding
抗原
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