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VAV1 抗体 (AA 121-324)

This anti-VAV1 antibody is a 小鼠 单克隆 antibody detecting VAV1 in WB, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN1845807
发货至: 中国
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Quick Overview for VAV1 抗体 (AA 121-324) (ABIN1845807)

抗原

See all VAV1 抗体
VAV1 (Vav 1 Oncogene (VAV1))

适用

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  • 42
  • 27
  • 2
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  • 1
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宿主

  • 67
  • 5
小鼠

克隆类型

  • 67
  • 5
单克隆

标记

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  • 2
  • 2
  • 2
  • 2
  • 2
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  • 1
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This VAV1 antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • 抗原表位

    • 15
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    • 7
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 121-324

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human VAV1 (AA: 121-324) expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    VAV1 (Vav 1 Oncogene (VAV1))

    别名

    VAV1

    背景

    The protein encoded by this proto-oncogene is a member of the Dbl family of guanine nucleotide exchange factors (GEF) for the Rho family of GTP binding proteins. The protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. This particular GEF has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication.

    分子量

    98.3 kDa

    基因ID

    7409

    UniProt

    P15498

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling
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