EGFR Mutant (AA 693-893), (Mutant) 抗体
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Quick Overview for EGFR Mutant (AA 693-893), (Mutant) 抗体 (ABIN1845729)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 693-893, Mutant
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纯化方法
- Purified antibody
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免疫原
- Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. coli.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
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- EGFR Mutant
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背景
- The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growth factor family.EGFR is a cell surface protein that binds to epidermal growth factor.Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.Mutations in this gene are associated with lung cancer.Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
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分子量
- 175 kDa
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基因ID
- 1956
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UniProt
- P00533
抗原
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