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EGFR Mutant (AA 693-893), (Mutant) 抗体

The 小鼠 单克隆 anti-EGFR Mutant antibody (ABIN1845729) specifically detects EGFR Mutant in ELISA, IHC, FACS 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN1845729
发货至: 中国
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Quick Overview for EGFR Mutant (AA 693-893), (Mutant) 抗体 (ABIN1845729)

抗原

EGFR Mutant

适用

宿主

  • 2
小鼠

克隆类型

  • 2
单克隆

标记

  • 2
非结合性

应用范围

ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Western Blotting (WB)
  • 抗原表位

    AA 693-893, Mutant

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    EGFR Mutant

    背景

    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growth factor family.EGFR is a cell surface protein that binds to epidermal growth factor.Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.Mutations in this gene are associated with lung cancer.Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

    分子量

    175 kDa

    基因ID

    1956

    UniProt

    P00533
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