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CD33 抗体 (AA 15-237)

This anti-CD33 antibody is a 小鼠 单克隆 antibody detecting CD33 in FACS, WB, IHC 和 ELISA. Suitable for 人.
产品编号 ABIN1845398
发货至: 中国

Quick Overview for CD33 抗体 (AA 15-237) (ABIN1845398)

抗原

See all CD33 抗体
CD33

适用

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宿主

  • 107
  • 90
  • 3
小鼠

克隆类型

  • 108
  • 91
  • 1
单克隆

标记

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This CD33 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 16
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    • 9
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    AA 15-237

    纯化方法

    Purified antibody

    免疫原

    Purified recombinant fragment of human CD33 (AA: 15-237) expressed in E. coli.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
  • 抗原

    CD33

    别名

    CD33

    背景

    The protein encoded by this gene belongs to putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells.Preferentially binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules.Induces apoptosis in acute myeloid leukemia (in vitro) and CD33 plays potential key roles in the pathogenesis of Alzheimer's disease (AD).

    分子量

    39.8 kDa

    基因ID

    945

    UniProt

    P20138
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