NEFH 抗体
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- 抗原 See all NEFH 抗体
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
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适用
- 人, 大鼠, 小鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NEFH antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Recognizes bovine intermediate 200 kD Neurofilament H (NFH), a 1026 amino acid ~200 kD protein involved in the maintenance of neuronal integrity. Neurofilaments are a major component of the cellular cytoskeleton, acting as the most abundant support for the axon cytoplasm. They exist as three neurofilament proteins: 68/70 kD (NFL) 160 kD (NFM) and 200 kD (NFH), which are expressed in both the central and peripheral nervous systems. Although typically expressed by neurons, neurofilaments are also expressed by neuroblastomas, neuromas, gangliogliomas, ganglioneuromas, and ganglioneuroblastomas, as well as paragangliomas, carcinoids, skin neuroendocrine carcinomas, and oat cell carcinomas of the lung. Defects in NFH are responsible for susceptibility to the neurodegenerative disorder amyotrophic lateral sclerosis (ALS) which affects upper and lower motor neurons, and results in fatal paralysis.
- 纯化方法
- Purified
- 免疫原
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GST-tagged bovine NFH recombinant protein.
Type of Immunogen: Recombinant protein - 亚型
- IgG
- Top Product
- Discover our top product NEFH Primary Antibody
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- 应用备注
- Approved: IHC, IHC-P (1 μg/mL), WB (0.1 μg/mL)
- 说明
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Target Species of Antibody: Bovine
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Tris-glycine buffered saline, sodium chloride, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- 抗原
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
- 别名
- NEFH / NF-H (NEFH 产品)
- 别名
- NF-H antibody, NF200 antibody, Nfh antibody, mKIAA0845 antibody, NFH antibody, NEFH antibody, neurofilament heavy polypeptide antibody, neurofilament, heavy polypeptide antibody, neurofilament heavy antibody, MCYG_06231 antibody, Nefh antibody, NEFH antibody
- 背景
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Name/Gene ID: NEFH
Synonyms: NEFH, 200 kDa neurofilament protein, KIAA0845, NFH, NF-H - 基因ID
- 4744
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