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NEFH 抗体

This 兔 多克隆 anti-NEFH antibody specifically detects NEFH in WB, IHC 和 IHC (p). The antibody is reactive with 人, 大鼠, 小鼠 和 Cow samples.
产品编号 ABIN1834898
发货至: 中国
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Quick Overview for NEFH 抗体 (ABIN1834898)

抗原

See all NEFH 抗体
NEFH (Neurofilament, Heavy Polypeptide (NEFH))

适用

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人, 大鼠, 小鼠, Cow

宿主

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克隆类型

  • 99
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多克隆

标记

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This NEFH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    Recognizes bovine intermediate 200 kD Neurofilament H (NFH), a 1026 amino acid ~200 kD protein involved in the maintenance of neuronal integrity. Neurofilaments are a major component of the cellular cytoskeleton, acting as the most abundant support for the axon cytoplasm. They exist as three neurofilament proteins: 68/70 kD (NFL) 160 kD (NFM) and 200 kD (NFH), which are expressed in both the central and peripheral nervous systems. Although typically expressed by neurons, neurofilaments are also expressed by neuroblastomas, neuromas, gangliogliomas, ganglioneuromas, and ganglioneuroblastomas, as well as paragangliomas, carcinoids, skin neuroendocrine carcinomas, and oat cell carcinomas of the lung. Defects in NFH are responsible for susceptibility to the neurodegenerative disorder amyotrophic lateral sclerosis (ALS) which affects upper and lower motor neurons, and results in fatal paralysis.

    纯化方法

    Purified

    免疫原

    GST-tagged bovine NFH recombinant protein.

    Type of Immunogen: Recombinant protein

    亚型

    IgG
  • 应用备注

    Approved: IHC, IHC-P (1 μg/mL), WB (0.1 μg/mL)

    说明

    Target Species of Antibody: Bovine

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Tris-glycine buffered saline, sodium chloride, 0.05 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    NEFH (Neurofilament, Heavy Polypeptide (NEFH))

    别名

    NEFH / NF-H

    背景

    Name/Gene ID: NEFH

    Synonyms: NEFH, 200 kDa neurofilament protein, KIAA0845, NFH, NF-H

    基因ID

    4744
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