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CD11b 抗体

This anti-CD11b antibody is a 大鼠 单克隆 antibody detecting CD11b in FACS, IHC, IP, IF, IHC (fro) 和 Func. Suitable for 人 和 小鼠.
产品编号 ABIN1820248
发货至: 中国

Quick Overview for CD11b 抗体 (ABIN1820248)

抗原

See all CD11b (ITGAM) 抗体
CD11b (ITGAM) (Integrin alpha M (ITGAM))

适用

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宿主

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大鼠

克隆类型

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单克隆

标记

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This CD11b antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

5C6
  • 特异性

    Recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. The antibody immunoprecipitates a heterodimer of 165 and 95kD. Clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes.

    纯化方法

    Protein G purified

    内毒素水平

    Low Endotoxin

    免疫原

    Thioglycollate-elicited Peritoneal Macrophages (TPM).

    亚型

    IgG2b
  • 应用备注

    Approved: Flo (1:50 - 1:100), Func, IF, IHC, IHC-Fr, IP

    Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

    说明

    Target Species of Antibody: Mouse

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze-thaw cycles.
  • 抗原

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    别名

    ITGAM / CD11b

    背景

    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

    基因ID

    3684

    途径

    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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