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ESR2 抗体 (AA 493-504)

This anti-ESR2 antibody is a 小鼠 单克隆 antibody detecting ESR2 in WB, IHC 和 IHC (p). Suitable for 人.
产品编号 ABIN1820030
发货至: 中国

Quick Overview for ESR2 抗体 (AA 493-504) (ABIN1820030)

抗原

See all ESR2 抗体
ESR2 (Estrogen Receptor 2 (ESR2))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ESR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5-25
  • 抗原表位

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    AA 493-504

    特异性

    Recognizes human estrogen receptor beta 5 (ERB5), a splice variant of the nuclear receptor hormone ERbeta (ESR2), shown to exist in at least five isoforms (ERB1-ERB5). Although only the ERB1 variant appears fully functional, the remaining isoforms have been shown to form heterodimers with ERB1, thereby enhancing transcription. Immunohistochemical studies have revealed a ubiquitous expression of ERB5 in normal colorectal tissue, and to be present in all primary colorectal carcinomas studied. Studies also revealed the nuclear expression of ERB5 in the majority of breast carcinomas tested, with a possible association with improved patient survival.

    纯化方法

    Protein G purified

    免疫原

    Tuberculin conjugated synthetic peptide LLSHVRHARYAP derived from the C-terminus of human ERB5. Percent identity by BLAST analysis: Human (100%), Ferret (92%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.1 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    ESR2 (Estrogen Receptor 2 (ESR2))

    别名

    ESR2 / ER beta

    背景

    Name/Gene ID: ESR2
    Subfamily: NR3 Steroid receptor
    Family: NHR

    Synonyms: ESR2, ESTRB, ER Beta, ERbeta, ER-BETA, ESR-BETA, ESRB, Estrogen receptor 2 (ER beta), NR3A2, Estrogen receptor beta, Estrogen receptor beta 4

    基因ID

    2100

    途径

    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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