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TREM1 抗体

The 大鼠 单克隆 anti-TREM1 antibody (Clone L5-B8-2A12-3A12) (ABIN6796407) specifically detects TREM1 in WB, FACS, IF 和 IHC (fro). The antibody is reactive with 小鼠 samples.
产品编号 ABIN6796407
发货至: 中国
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Quick Overview for TREM1 抗体 (ABIN6796407)

抗原

See all TREM1 抗体
TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This TREM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

L5-B8-2A12-3A12
  • 特异性

    Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.

    纯化方法

    Protein G purified

    免疫原

    Mouse TREM-1 Fc fusion protein.
    Immunogen type: Fusion protein

    亚型

    IgG2a
  • 应用备注

    Flo (1:25 - 1:100), IF, IHC-Fr, WB

    限制

    仅限研究用
  • 浓度

    Lot specific

    缓冲液

    PBS, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C
  • 抗原

    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))

    别名

    TREM1 / TREM-1

    背景

    Synonyms :
    TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1

    基因ID

    54210

    UniProt

    Q9NP99
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