TREM1 抗体
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北京 101111
Quick Overview for TREM1 抗体 (ABIN6796407)
抗原
See all TREM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
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纯化方法
- Protein G purified
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免疫原
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Mouse TREM-1 Fc fusion protein.
Immunogen type: Fusion protein -
亚型
- IgG2a
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应用备注
- Flo (1:25 - 1:100), IF, IHC-Fr, WB
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限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
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别名
- TREM1 / TREM-1
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背景
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Synonyms :
TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1 -
基因ID
- 54210
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UniProt
- Q9NP99
抗原
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