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TREM1 抗体

TREM1 适用: 小鼠 WB, FACS, IHC (fro), IF 宿主: 大鼠 Monoclonal L5-B8-2A12-3A12 unconjugated
产品编号 ABIN1819860
发货至: 中国
  • 抗原 See all TREM1 抗体
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    适用
    • 70
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    小鼠
    宿主
    • 79
    • 18
    • 7
    大鼠
    克隆类型
    • 80
    • 22
    • 1
    单克隆
    标记
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    This TREM1 antibody is un-conjugated
    应用范围
    • 81
    • 49
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    • 9
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
    特异性
    Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
    纯化方法
    Protein G purified
    免疫原
    Mouse TREM-1 Fc fusion protein.
    Immunogen type: Fusion protein
    克隆位点
    L5-B8-2A12-3A12
    亚型
    IgG2a
    Top Product
    Discover our top product TREM1 Primary Antibody
  • 应用备注
    Flo (1:25 - 1:100), IF, IHC-Fr, WB
    限制
    仅限研究用
  • 浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
  • 抗原
    TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
    别名
    TREM1 / TREM-1 (TREM1 产品)
    背景
    Synonyms :
    TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1
    基因ID
    54210
    UniProt
    Q9NP99
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