TREM1 抗体
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北京 101111
Quick Overview for TREM1 抗体 (ABIN1819858)
抗原
See all TREM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
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纯化方法
- Protein G purified
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免疫原
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Mouse TREM-1 Fc fusion protein.
ImmunogenType: Fusion protein -
亚型
- IgG2a
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应用备注
- Flo (1:25 - 1:100) IF, IHC-Fr
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限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store at -20°C.
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- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
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别名
- TREM1
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背景
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Synonyms :
TREM1, CD354, CD354 antigen, Triggering-receptor TREM1, TREM-1 -
基因ID
- 54210
抗原
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