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DC-SIGN/CD209 抗体 (PE)

The 小鼠 单克隆 anti-DC-SIGN/CD209 antibody is suitable to detect DC-SIGN/CD209 in samples from 人. It has been validated for FACS.
产品编号 ABIN181976
发货至: 中国
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Room 801-803
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Quick Overview for DC-SIGN/CD209 抗体 (PE) (ABIN181976)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

MR-1
  • 特异性

    This antibody recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 which is also known as CD209. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. We recommend the use of SM2219LE for this purpose.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Immature myeloid monocyte-derived dendritic cells (MDDCs). Spleen cells from immunised Balb/c mice were fused with cells of the Mouse SP2/0-Ag14 myeloma cell line.

    亚型

    IgG1
  • 应用备注

    Flow Cytometry (Neat-1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL distilled water

    浓度

    0.1 mg/mL

    缓冲液

    PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    This product is photosensitive and should be protected from light

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    CD209 / DC-SIGN

    背景

    CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

    基因ID

    9606

    UniProt

    Q9NNX6
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