DC-SIGN/CD209 抗体 (PE)
Quick Overview for DC-SIGN/CD209 抗体 (PE) (ABIN181976)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 which is also known as CD209. Clone MR-1 is reported to partially block the functional activity of DC-SIGN. We recommend the use of SM2219LE for this purpose.
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Immature myeloid monocyte-derived dendritic cells (MDDCs). Spleen cells from immunised Balb/c mice were fused with cells of the Mouse SP2/0-Ag14 myeloma cell line.
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亚型
- IgG1
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应用备注
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Flow Cytometry (Neat-1/10): Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1 mL distilled water
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浓度
- 0.1 mg/mL
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缓冲液
- PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- This product is photosensitive and should be protected from light
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
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- DC-SIGN/CD209 (CD209) (CD209)
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别名
- CD209 / DC-SIGN
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背景
- CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's.Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
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基因ID
- 9606
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UniProt
- Q9NNX6
抗原
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