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DC-SIGN/CD209 抗体

The 小鼠 单克隆 anti-DC-SIGN/CD209 antibody (Clone MR-1) (ABIN181974) specifically detects DC-SIGN/CD209 in FACS, IF 和 Func. The antibody is reactive with 人 samples.
产品编号 ABIN181974
发货至: 中国
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Quick Overview for DC-SIGN/CD209 抗体 (ABIN181974)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This DC-SIGN/CD209 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

克隆位点

MR-1
  • 特异性

    This antibodies recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 also known as CD209.

    纯化方法

    Protein G affinity chromatography

    内毒素水平

    Low Endotoxin

    免疫原

    Immature myeloid monocyte-derived dendritic cells (MDDCs)

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Use 10 μL to label 10^6 cells in 100 μL. Immunofluorescence. Functional assays.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH 7.4, without preservatives or stbilizers

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

    有效期

    6 months
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    CD209 / DC-SIGN

    背景

    CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

    基因ID

    9606

    UniProt

    Q9NNX6
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