DC-SIGN/CD209 抗体
Quick Overview for DC-SIGN/CD209 抗体 (ABIN181974)
抗原
See all DC-SIGN/CD209 (CD209) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibodies recognises human DC-specific ICAM-3 grabbing nonintegrin (DC-SIGN), a 45 kDa C-type lectin that binds ICAM-3 also known as CD209.
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纯化方法
- Protein G affinity chromatography
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内毒素水平
- Low Endotoxin
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免疫原
- Immature myeloid monocyte-derived dendritic cells (MDDCs)
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亚型
- IgG1
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应用备注
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Flow cytometry: Use 10 μL to label 10^6 cells in 100 μL. Immunofluorescence. Functional assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.4, without preservatives or stbilizers
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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有效期
- 6 months
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- DC-SIGN/CD209 (CD209) (CD209)
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别名
- CD209 / DC-SIGN
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背景
- CD209 is primarily expressed on a population of immature dendritic cells in peripheral tissues and on immature myeloid monocyte-derived DC's in vitro. CD209 is involved in dendritic cell (DC) migration and the initial interaction between DC's and naive T lymphocytes. CD209 also binds HIV-1 gp120 and plays a key role in the dissemination of HIV-1 by DC's. Clone MR-1 is reported to partially block the functional activity of DC-SIGN(2).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1
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基因ID
- 9606
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UniProt
- Q9NNX6
抗原
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