MAP1LC3A 抗体 (AA 2-15)
Quick Overview for MAP1LC3A 抗体 (AA 2-15) (ABIN1819535)
抗原
See all MAP1LC3A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-15
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特异性
- Recognizes an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B), ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy. LC3-I is the cytosolic form of LC3, which is converted into the active, membrane-bound form LC3-II, during the autophagy process. Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with the autophagosome membrane. Recognizes both the LC3-I and LC3-II forms of MAP1LC3A and MAP1LC3B.
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纯化方法
- Affinity purified
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免疫原
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Synthetic peptide sequence PSDRPFKQRRSFADC from the N-Terminal region of LC3A (NP_115903.1, NP_852610.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Bovine, Pig, Opossum, Guinea pig, Salmon, Zebrafish (100%), Ferret, Dog, Cat, Lizard, Catfish, Stickleback, Medaka, Pufferfish (93%), Chicken, Pike (86%).
Type of Immunogen: Synthetic peptide -
亚型
- IgG
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应用备注
- Approved: IF, WB (1:100 - 1:250)
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说明
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Target Species of Antibody: Human
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- PBS, 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
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别名
- MAP1LC3A / LC3A
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背景
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Name/Gene ID: MAP1LC3A
Synonyms: MAP1LC3A, ATG8E, LC3, LC3A, MAP1BLC3, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3 -
基因ID
- 84557
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NCBI登录号
- NP_115903, NP_852610
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途径
- Autophagy
抗原
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