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MAP1LC3A 抗体 (AA 2-15)

This anti-MAP1LC3A antibody is a 兔 多克隆 antibody detecting MAP1LC3A in WB 和 IF. Suitable for 人, 小鼠, 大鼠, 斑马鱼, Cow, 豚鼠, 猴, Pig 和 鱼.
产品编号 ABIN1819535
发货至: 中国

Quick Overview for MAP1LC3A 抗体 (AA 2-15) (ABIN1819535)

抗原

See all MAP1LC3A 抗体
MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

适用

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人, 小鼠, 大鼠, 斑马鱼, Cow, 豚鼠, 猴, Pig, 鱼

宿主

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克隆类型

  • 126
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多克隆

标记

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This MAP1LC3A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF)
  • 抗原表位

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    AA 2-15

    特异性

    Recognizes an epitope within the N-Terminal (NT) region of both MAP1LC3A (Microtubule-associated proteins 1A/1B light chain 3A/LC3A) and MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B/LC3B), ubiquitin-like proteins and members of the MAP1LC3 family, which are widely used as reliable markers for the monitoring of autophagy. LC3-I is the cytosolic form of LC3, which is converted into the active, membrane-bound form LC3-II, during the autophagy process. Tracking the level of conversion of LC3-I to LC3-II provides an indicator of autophagic activity, and levels of LC3-II in particular, correlate with the extent of autophagosome formation, due to its association with the autophagosome membrane. Recognizes both the LC3-I and LC3-II forms of MAP1LC3A and MAP1LC3B.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide sequence PSDRPFKQRRSFADC from the N-Terminal region of LC3A (NP_115903.1, NP_852610.1). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Monkey, Galago, Marmoset, Mouse, Rat, Bovine, Pig, Opossum, Guinea pig, Salmon, Zebrafish (100%), Ferret, Dog, Cat, Lizard, Catfish, Stickleback, Medaka, Pufferfish (93%), Chicken, Pike (86%).

    Type of Immunogen: Synthetic peptide

    亚型

    IgG
  • 应用备注

    Approved: IF, WB (1:100 - 1:250)

    说明

    Target Species of Antibody: Human

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    PBS, 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原

    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

    别名

    MAP1LC3A / LC3A

    背景

    Name/Gene ID: MAP1LC3A

    Synonyms: MAP1LC3A, ATG8E, LC3, LC3A, MAP1BLC3, MAP1A/1B light chain 3 A, MAP1A/MAP1B LC3 A, MAP1A/MAP1B light chain 3 A, MAP1ALC3

    基因ID

    84557

    NCBI登录号

    NP_115903, NP_852610

    途径

    Autophagy
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