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KIT 抗体

KIT 适用: Pig WB, FACS, IHC, IP, IHC (fro) 宿主: 小鼠 Monoclonal 2B8-BM unconjugated
产品编号 ABIN1819120
发货至: 中国
  • 抗原 See all KIT 抗体
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    适用
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    • 222
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    Pig
    宿主
    • 518
    • 94
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    • 1
    小鼠
    克隆类型
    • 510
    • 136
    • 1
    单克隆
    标记
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    This KIT antibody is un-conjugated
    应用范围
    • 352
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    Porcine CD117, also known as c-kit, a 155kD type I transmembrane protein with protein tyrosine kinase activity, which plays an important role in early hematopoiesis. Hematopoietic stem cells (HSC) of bone marrow have multilineage differentiation potential and an extensive capacity for self-renewal. The majority of adult bone marrow hematopoietic progenitor cells are CD117+ and have been used successfully in xenograft transplantation models for long term survival of grafts, without symptoms of graft-versus-host disease (GVHD). Recognizes CD117 on a small subset of porcine bone marrow progenitor cells and therefore provides an alternative tool from the previously used c-kit ligand stem cell factor, for the isolation and enrichment of porcine stem cells.
    纯化方法
    Protein G purified
    免疫原
    Porcine bone marrow cells (BMC).
    克隆位点
    2B8-BM
    亚型
    IgG1
    Top Product
    Discover our top product KIT Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    Target Species of Antibody: Pig

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    PBS, 0.09 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    4°C or -20°C, Avoid freeze-thaw cycles.
  • 抗原
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    别名
    C-Kit / CD117 (KIT 产品)
    背景
    Name/Gene ID: KIT
    Subfamily: PDGF Receptor
    Family: Protein Kinase

    Synonyms: KIT, C-Kit, CD117, PBT, Piebald trait, Piebald trait protein, Proto-oncogene c-Kit, SCFR, Soluble KIT variant 1, Tyrosine-protein kinase Kit, p145 c-kit, CD117 antigen
    基因ID
    3815
    UniProt
    P10721
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
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