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Interferon gamma 抗体

This 小鼠 单克隆 antibody specifically detects Interferon gamma in EIA 和 IHC (fro). It exhibits reactivity toward 小鼠 和 大鼠.
产品编号 ABIN181786
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Interferon gamma 抗体 (ABIN181786)

抗原

See all Interferon gamma (IFNG) 抗体
Interferon gamma (IFNG)

适用

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小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This Interferon gamma antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

DB1
  • 特异性

    This antibody reacts with IFN-gamma. Clone DB-1 exhibits high affinity binding to the natural and recombinant forms and effectively neutralises the anti viral activity of IFN-gamma. It also blocks the induction of Ia antigen expression on murine keratinocytes. There is no cross-reaction with rodent IFN-alpha or IFN-beta or with human interferons. Clone DB-1 has also been reported for use in neutralising studies. MCA1301XZ is recommended for this purpose.

    纯化方法

    Purified

    免疫原

    Recombinant rat IFN gamma.

    亚型

    IgG1
  • 应用备注

    ELISA: 10 μg/mL - 100 μg/mL. Immunohistochemistry on frozen sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 125 mM trehalose and 0.09 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Interferon gamma (IFNG)

    别名

    IFNG / Interferon gamma

    背景

    Interferon gamma is mainly produced by T lymphocytes and NK cells. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses,including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak antiviral and antiproliferative activity, and poteniates the antiviral and anti tumor effects of IFN alpha / beta (type I interferon). It is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN. Labile at pH 2.Synonyms: IFN-gamma, gamma IFN

    基因ID

    15978

    NCBI登录号

    NP_032363

    UniProt

    P01580

    途径

    Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy
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