Galectin 3 抗体 (Biotin)
Quick Overview for Galectin 3 抗体 (Biotin) (ABIN181681)
抗原
See all Galectin 3 (LGALS3) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity Chromatography.
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免疫原
- Highly pure (> 98%) recombinant human Galectin-3
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应用备注
- ELISADirect: To detect hGalectin-3 (using 100 μL/well antibody solution) a concentration ofapprox. 1.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, allows the detection of at least 0.2-0.4 ng/well of recombinant HumanGalectin-3. Sandwich: To detect Human Galectin-3 (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. In conjunction with PolyclonalAnti-Human Galectin-3 (ABIN181683 or ABIN181684) as a capture antibody, it allows thedetection of at least 0.2-0.4 ng/well of recombinant Human Galectin-3. Western blot
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限制
- 仅限研究用
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溶解方式
- Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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有效期
- 6 months
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- Galectin 3 (LGALS3)
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别名
- Galectin-3
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物质类
- Chemical
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背景
- Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas. Conversely, it is down-regulated in other cancers, such as colon, breast, ovarian, and uterine.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2
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基因ID
- 9606
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UniProt
- P17931
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途径
- RTK signaling
抗原
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