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APOE 抗体 (Isoform E3)

APOE 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN181668
发货至: 中国
  • 抗原 See all APOE 抗体
    APOE (Apolipoprotein E (APOE))
    抗原表位
    • 15
    • 15
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Isoform E3
    适用
    • 100
    • 75
    • 56
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 100
    • 22
    • 14
    • 2
    克隆类型
    • 104
    • 33
    多克隆
    标记
    • 57
    • 18
    • 12
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APOE antibody is un-conjugated
    应用范围
    • 109
    • 58
    • 39
    • 39
    • 30
    • 24
    • 19
    • 12
    • 9
    • 8
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ApoE3. Cross reacts with ApoE2 and ApoE4.
    纯化方法
    Immunoaffinity chromatography
    免疫原
    Highly pure (> 98 %) recombinant human ApoE3
    Top Product
    Discover our top product APOE Primary Antibody
  • 应用备注
    ELISA: Indirect: To detect hApoE3 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hApoE3. Sandwich: To detect hApoE3 (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with Biotinylated Anti-HumanApoE3 as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hApoE3. Western blot: To detect hApoE3 this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hApoE3 is 1.5 - 3.0 ng/lane, under either reducing or non-reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1 - 1.0 mg/mL.
    缓冲液
    PBS, pH 7.2
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2 - 8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
    有效期
    6 months
  • 抗原
    APOE (Apolipoprotein E (APOE))
    别名
    Apolipoprotein E (Apo E) (APOE 产品)
    别名
    ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
    背景
    Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE
    基因ID
    348
    NCBI登录号
    NP_000032
    UniProt
    P02649
    途径
    Regulation of Cell Size, Lipid Metabolism
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