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APOE 抗体 (AA 55-294)

APOE 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886470
发货至: 中国
  • 抗原 See all APOE 抗体
    APOE (Apolipoprotein E (APOE))
    抗原表位
    • 15
    • 15
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 55-294
    适用
    • 100
    • 74
    • 55
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠, 大鼠
    宿主
    • 100
    • 22
    • 13
    • 2
    克隆类型
    • 103
    • 33
    多克隆
    标记
    • 57
    • 18
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    This APOE antibody is un-conjugated
    应用范围
    • 108
    • 57
    • 39
    • 39
    • 30
    • 23
    • 19
    • 12
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Apolipoprotein E(APOE) detection. Tested with WB, IHC-P in Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Apolipoprotein E(APOE) detection. Tested with WB, IHC-P in Mouse,Rat.
    Gene Name: apolipoprotein E
    Protein Name: Apolipoprotein E
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived mouse Apolipoprotein E recombinant protein (Position: D55-Q294). Mouse Apolipoprotein E shares 75% and 94.6% amino acid (aa) sequence identity with human and rat Apolipoprotein E, respectively.
    亚型
    IgG
    Top Product
    Discover our top product APOE Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    APOE (Apolipoprotein E (APOE))
    别名
    APOE (APOE 产品)
    别名
    ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
    背景
    APOE is also known as AD2 or LPG. The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants.

    Synonyms: AD2 | Apo E | APOE | Apo-E | Apolipoprotein E | Apolipoprotein E3 | LPG | P08226
    基因ID
    11816
    UniProt
    P08226
    途径
    Regulation of Cell Size, Lipid Metabolism
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