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CCL19 抗体

This anti-CCL19 antibody is a 小鼠 单克隆 antibody detecting CCL19 in EIA. Suitable for 人.
产品编号 ABIN181150
发货至: 中国

Quick Overview for CCL19 抗体 (ABIN181150)

抗原

See all CCL19 抗体
CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CCL19 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)
  • 特异性

    This antibody detects MIP-3 beta.

    产品特性

    Synonyms: C-C motif chemokine 19, CCL-19, ELC, MIP3B, MIP-3 beta, Small-inducible cytokine A19,SCYA19, Exodus-3, Small-inducible cytokine A19, EBI1-ligand chemokine, Beta chemokineexodus-3, CK beta-11, Macrophage inflammatory protein 3 beta

    纯化方法

    Protein A chromatography

    免疫原

    Recombinant human MIP-3-beta

    亚型

    IgG1
  • 应用备注

    ELISA: In a sandwich ELISA (assuming 100 l/well), a concentration of 2-3 μg/mL of thisantibody will detect at least 0.2 ng/well of recombinant human MIP-3-beta when used withbiotinylated antigen affinity purified anti-human MIP-3-beta as the detection antibody at aconcentration of at least 0.5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of 1 mg/mL.

    储存液

    Azide free

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2 - 8 °C for six weeks. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

    别名

    MIP3-beta / CCL19

    背景

    MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30 % aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13.Synonyms: Beta chemokine exodus-3, C-C motif chemokine 19, CCL-19, CK beta-11, EBI1-ligand chemokine, ELC, Exodus-3, MIP-3 beta, MIP3B, Macrophage inflammatory protein 3 beta, SCYA19, Small-inducible cytokine A19, Small-inducible cytokine A19

    基因ID

    6363

    UniProt

    Q99731

    途径

    Positive Regulation of Immune Effector Process
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