CCL19 抗体
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北京 101111
Quick Overview for CCL19 抗体 (ABIN181150)
抗原
See all CCL19 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects MIP-3 beta.
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产品特性
- Synonyms: C-C motif chemokine 19, CCL-19, ELC, MIP3B, MIP-3 beta, Small-inducible cytokine A19,SCYA19, Exodus-3, Small-inducible cytokine A19, EBI1-ligand chemokine, Beta chemokineexodus-3, CK beta-11, Macrophage inflammatory protein 3 beta
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纯化方法
- Protein A chromatography
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免疫原
- Recombinant human MIP-3-beta
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亚型
- IgG1
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应用备注
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ELISA: In a sandwich ELISA (assuming 100 l/well), a concentration of 2-3 μg/mL of thisantibody will detect at least 0.2 ng/well of recombinant human MIP-3-beta when used withbiotinylated antigen affinity purified anti-human MIP-3-beta as the detection antibody at aconcentration of at least 0.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 1 mg/mL.
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储存液
- Azide free
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储存条件
- 4 °C/-20 °C
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储存方法
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The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2 - 8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))
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别名
- MIP3-beta / CCL19
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背景
- MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30 % aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13.Synonyms: Beta chemokine exodus-3, C-C motif chemokine 19, CCL-19, CK beta-11, EBI1-ligand chemokine, ELC, Exodus-3, MIP-3 beta, MIP3B, Macrophage inflammatory protein 3 beta, SCYA19, Small-inducible cytokine A19, Small-inducible cytokine A19
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基因ID
- 6363
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UniProt
- Q99731
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途径
- Positive Regulation of Immune Effector Process
抗原
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