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BMP4 抗体

BMP4 适用: 人 WB, IF, EIA, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN181146
发货至: 中国
  • 抗原 See all BMP4 抗体
    BMP4 (Bone Morphogenetic Protein 4 (BMP4))
    适用
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    宿主
    • 86
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    小鼠
    克隆类型
    • 94
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    单克隆
    标记
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    This BMP4 antibody is un-conjugated
    应用范围
    • 95
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    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody detects BMP4.
    产品特性
    Synonyms: BMP2B, BMP-2B, BMP-4, DVR4, Bone morphogenetic protein 4
    纯化方法
    Affinity Chromatography on Protein G
    免疫原
    Highly pure (>98%) recombinant Human BMP-4
    亚型
    IgG2b
    Top Product
    Discover our top product BMP4 Primary Antibody
  • 应用备注
    ELISA: In a sandwich ELISA (assuming 100μL/well), a concentration of 4.0-8.0 μg/mL of thisantibody will detect at least 2000 pg/mL of recombinant Human BMP-4 when used inconjunction with compatible secondary reagents. Western Blot: To detect Human BMP-4 by Western Blot analysis this antibody can be usedat a concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant Human BMP-4 is 2.0-4.0 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhBMP-4 (5.0 ng/mL), a concentration of 0.4-0.6 μg/mL of this antibody is required.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 1.0 mg/mL.
    缓冲液
    PBS without preservatives
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2-8 °C for six weeks. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    BMP4 (Bone Morphogenetic Protein 4 (BMP4))
    别名
    BMP4 (BMP4 产品)
    别名
    BMP2B antibody, BMP2B1 antibody, MCOPS6 antibody, OFC11 antibody, ZYME antibody, Bmp-4 antibody, Bmp2b antibody, Bmp2b-1 antibody, Bmp2b1 antibody, BOMPR4A antibody, bmp-4 antibody, zbmp-4 antibody, zgc:100779 antibody, BMP-4 antibody, XBMP-4 antibody, bmp2b antibody, bmp2b1 antibody, bmp4 antibody, ofc11 antibody, xbmp4 antibody, zyme antibody, BMP4 antibody, bone morphogenetic protein 4 antibody, bone morphogenetic protein 4 L homeolog antibody, bone morphogenetic protein 4 S homeolog antibody, BMP4 antibody, Bmp4 antibody, bmp4 antibody, bmp4.L antibody, bmp4.S antibody
    背景
    BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.Synonyms: BMP-2B, BMP-4, BMP2B, Bone morphogenetic protein 4, DVR4
    基因ID
    652
    UniProt
    P12644
    途径
    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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