BMP4 抗体
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北京 101111
Quick Overview for BMP4 抗体 (ABIN181146)
抗原
See all BMP4 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects BMP4.
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产品特性
- Synonyms: BMP2B, BMP-2B, BMP-4, DVR4, Bone morphogenetic protein 4
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Highly pure (>98%) recombinant Human BMP-4
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亚型
- IgG2b
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anti-Bone Morphogenetic Protein 4 (BMP4) (C-Term) antibody
BMP4 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC 宿主: 小鼠 Monoclonal 3C11H8 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 277-408) antibodyBMP4 适用: 人, 大鼠 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C11C7 unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 1-408) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 303-408) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 5-34) antibodyBMP4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 22-408) antibodyBMP4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Bone Morphogenetic Protein 4 (BMP4) (AA 23-204) antibody (APC)BMP4 适用: 兔 WB, IHC, IP, ICC 宿主: 豚鼠 Polyclonal APC
anti-Bone Morphogenetic Protein 4 (BMP4) antibodyBMP4 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
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应用备注
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ELISA: In a sandwich ELISA (assuming 100μL/well), a concentration of 4.0-8.0 μg/mL of thisantibody will detect at least 2000 pg/mL of recombinant Human BMP-4 when used inconjunction with compatible secondary reagents. Western Blot: To detect Human BMP-4 by Western Blot analysis this antibody can be usedat a concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant Human BMP-4 is 2.0-4.0 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhBMP-4 (5.0 ng/mL), a concentration of 0.4-0.6 μg/mL of this antibody is required.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 1.0 mg/mL.
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缓冲液
- PBS without preservatives
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储存液
- Without preservative
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储存条件
- 4 °C/-20 °C
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储存方法
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The lyophilized antibody is stable at room temperature for one month or at -20 °C forlonger. Following reconstitution it is stable at 2-8 °C for six weeks. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- BMP4 (Bone Morphogenetic Protein 4 (BMP4))
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别名
- BMP4
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背景
- BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.Synonyms: BMP-2B, BMP-4, BMP2B, Bone morphogenetic protein 4, DVR4
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基因ID
- 652
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UniProt
- P12644
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途径
- Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
抗原
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