C6 抗体
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北京 101111
Quick Overview for C6 抗体 (ABIN181137)
抗原
See all C6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes complement component 6 (C6). This antibody recognizes MAC.
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产品特性
- Synonyms: Complement component C6, Complement 6
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Purified Human C6
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亚型
- IgG1
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应用备注
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ELISA. Flow Cytometry. Immunohistochemistry on Frozen Sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Borate buffered saline pH 8.2-8.4 containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- C6 (Complement Component 6 (C6))
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别名
- Complement C6
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背景
- C6 is a 104 kDa member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection.
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基因ID
- 729
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UniProt
- P13671
抗原
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