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Complement Factor B 抗体 (Fragment Ba)

CFB 适用: 人 WB, FACS, EIA, IHC (fro), Func 宿主: 小鼠 Monoclonal 014III-33-2-4-3 unconjugated
产品编号 ABIN181128
发货至: 中国
  • 抗原 See all Complement Factor B (CFB) 抗体
    Complement Factor B (CFB)
    抗原表位
    • 15
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    • 2
    • 1
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    Fragment Ba
    适用
    • 70
    • 44
    • 35
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 91
    • 14
    • 2
    小鼠
    克隆类型
    • 92
    • 14
    • 1
    单克隆
    标记
    • 45
    • 19
    • 15
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    This Complement Factor B antibody is un-conjugated
    应用范围
    • 80
    • 39
    • 30
    • 15
    • 13
    • 13
    • 12
    • 10
    • 8
    • 6
    • 5
    • 4
    • 2
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    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    特异性
    This antibody recognises the 30 kDa Ba fragment of 90 kDa complement factor B, present in blood serum.
    产品特性
    Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    Purified human complement factor b.
    克隆位点
    014III-33-2-4-3
    亚型
    IgG1
    Top Product
    Discover our top product CFB Primary Antibody
  • 应用备注
    Western Blot. Functional Assays. Flow Cytometry. ELISA: This antibody binds both the Ba fragment and the whole protein so is not suitablefor all ELISA applications. Immunohistochemistry on frozen sections. Recommended Positiv Control: Kidney from post streptoccal glomerulonephritis patients.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0mg/mL
    缓冲液
    Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    Complement Factor B (CFB)
    别名
    Complement Factor B (CFB 产品)
    别名
    AHUS4 antibody, BF antibody, BFD antibody, CFAB antibody, FB antibody, FBI12 antibody, GBG antibody, H2-Bf antibody, PBF2 antibody, bf antibody, Bf-1 antibody, Brre-Bf antibody, zgc:114032 antibody, Bf antibody, Sp152 antibody, bfb-A antibody, Bf B antibody, LOC397725 antibody, bf/c2 antibody, CFB antibody, AI195813 antibody, AI255840 antibody, B antibody, C2 antibody, Fb antibody, Da1-24 antibody, complement factor B antibody, complement factor B S homeolog antibody, complement factor B L homeolog antibody, CFB antibody, cfb antibody, bf antibody, cfb.S antibody, cfb.L antibody, bf/c2 antibody, LOC100555981 antibody, Cfb antibody
    背景
    C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B
    基因ID
    629
    UniProt
    P00751
    途径
    Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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