Complement Factor B 抗体 (Fragment Ba)
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- 抗原 See all Complement Factor B (CFB) 抗体
- Complement Factor B (CFB)
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抗原表位
- Fragment Ba
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Complement Factor B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 特异性
- This antibody recognises the 30 kDa Ba fragment of 90 kDa complement factor B, present in blood serum.
- 产品特性
- Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein
- 纯化方法
- Affinity chromatography on Protein A
- 免疫原
- Purified human complement factor b.
- 克隆位点
- 014III-33-2-4-3
- 亚型
- IgG1
- Top Product
- Discover our top product CFB Primary Antibody
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- 应用备注
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Western Blot. Functional Assays. Flow Cytometry. ELISA: This antibody binds both the Ba fragment and the whole protein so is not suitablefor all ELISA applications. Immunohistochemistry on frozen sections. Recommended Positiv Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0mg/mL
- 缓冲液
- Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Complement Factor B (CFB)
- 别名
- Complement Factor B (CFB 产品)
- 背景
- C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B
- 基因ID
- 629
- UniProt
- P00751
- 途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
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