Complement Factor B 抗体 (Fragment Ba)
Quick Overview for Complement Factor B 抗体 (Fragment Ba) (ABIN181128)
抗原
See all Complement Factor B (CFB) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Fragment Ba
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特异性
- This antibody recognises the 30 kDa Ba fragment of 90 kDa complement factor B, present in blood serum.
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产品特性
- Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein
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纯化方法
- Affinity chromatography on Protein A
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免疫原
- Purified human complement factor b.
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亚型
- IgG1
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应用备注
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Western Blot. Functional Assays. Flow Cytometry. ELISA: This antibody binds both the Ba fragment and the whole protein so is not suitablefor all ELISA applications. Immunohistochemistry on frozen sections. Recommended Positiv Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0mg/mL
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缓冲液
- Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Complement Factor B (CFB)
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别名
- Complement Factor B
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背景
- C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit), leaving the 63 kDa Bb subunit associated with C3b, forming C3 convertase. Subunit Ba inhibits lymphocyte proliferation. Conversely, subunit Bb is involved in the proliferation of preactivated B lymphocytes.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B
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基因ID
- 629
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UniProt
- P00751
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途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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