Complement Factor I 抗体
Our Local Distributor
北京 101111
Quick Overview for Complement Factor I 抗体 (ABIN181115)
抗原
See all Complement Factor I (CFI) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- This antibody recognises complement factor I, a member of the peptidase S1 family present in the blood plasma.
-
产品特性
- Synonyms: CFI, IF, KAF, AHUS3, C3BINA, C3b-INA, C3B/C4B inactivator
-
纯化方法
- Affinity chromatography on Protein A
-
免疫原
- Native human factor I from serum.
-
亚型
- IgG1
-
-
anti-Complement Factor I (CFI) (AA 28-243) antibody
CFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 358-603) antibodyCFI 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Complement Factor I (CFI) (AA 239-316) antibodyCFI 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (Internal Region) antibodyCFI 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 340-583) antibodyCFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-300) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA: 1/3000 - 1/4000. Western Blot. Functional Assays. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0mg/mL
-
缓冲液
- Borate buffered saline pH 8.4 containing 0.02 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
-
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
-
-
- Complement Factor I (CFI)
-
别名
- Complement Factor I
-
背景
- Factor I is an 88 kDa protein consisting of one polypeptide chain of 35.4 kDa and one of 27.6 kDa. Factor I is a serine protease which inactivates complement components C3b and C4b. C3b cleavage requires the presence of cofactors complement component (3b/4b) receptor 1 (CR1), membrane cofactor protein or factor H, while C4b cleavage requires complement component 4 binding protein or CR1. Factor I has no natural inhibitors. Dysfunctional factor I can lead to uncontrolled activation of the alternative complement pathway causing in systemic depletion of C3 and lower levels of factors B and H, resulting in recurrent pyogenic infections. Defects in CFI are also associated with haemolytic uraemic syndrome.Synonyms: AHUS3, C3B/C4B inactivator, C3BINA, C3b-INA, CFI, IF, KAF
-
基因ID
- 3426
-
UniProt
- P05156
-
途径
- Complement System
抗原
-
