Complement Factor H 抗体
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- 抗原 See all Complement Factor H (CFH) 抗体
- Complement Factor H (CFH)
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Complement Factor H antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
- 特异性
- This antibody recognises Complement Factor H which exists in 2 forms.
- 产品特性
- Synonyms: CFH, HF, HF1, HF2, H factor 1
- 纯化方法
- Affinity Chromatography on Protein A.
- 免疫原
- Purified human factor H from serum.
- 克隆位点
- 10-10-14
- 亚型
- IgG1
- Top Product
- Discover our top product CFH Primary Antibody
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anti-Complement Factor H (CFH) (AA 20-270) antibody
CFH 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 915-1156) antibodyCFH 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (Internal Region) antibodyVerified CFH 适用: 人 WB, IHC, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 860-1231) antibodyCFH 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 975-1217) antibodyCFH 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 751-780) antibodyCFH 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB18698 unconjugated
anti-Complement Factor H (CFH) (N-Term) antibodyCFH 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 20-270) antibodyCFH 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 1-449) antibodyCFH 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor H (CFH) (AA 751-780), (Middle Region) antibodyCFH 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot. Flow Cytometry. Immunohistochemistry on Frozen Sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Borate buffered saline pH 8.4 containing 0.02 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Complement Factor H (CFH)
- Abstract
- CFH 产品
- 背景
- Complement factor H exists in 2 forms, the most common form, of 150 kDa, and the less common form of 43 kDa. Factor H is secreted by the liver into the blood serum. It is important in regulating the complement pathway, preventing unnecessary inflammation which can damage the host tissue. Factor H functions as a cofactor in the inactivation of C3b by factor I. It makes C3b susceptible to cleavage by factor I, resulting in iC3b. Factor H also inhibits the formation of the C3bBb complex (C3 convertase) and increases the rate of dissociation of both C3 convertase and the (C3b)NBB complex (C5 convertase). This prevents these components of the classical and of alternative complement pathways from forming a positive feedback loop. Mutations in factor H are associated with hemolytic-uremic syndrome, age-related macular degeneration, membranoproliferative glomerulonephritis (MPGN) type II and chronic hypocomplementemic nephropathy.Synonyms: CFH, H factor 1, HF, HF1, HF2
- 基因ID
- 3075
- UniProt
- P08603
- 途径
- Complement System, Cellular Response to Molecule of Bacterial Origin
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