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C4BPA 抗体

C4BPA 适用: 人 IHC (p), EIA 宿主: 小鼠 Monoclonal 10-07-14 unconjugated
产品编号 ABIN181109
发货至: 中国
  • 抗原 See all C4BPA 抗体
    C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))
    适用
    • 37
    • 4
    • 1
    宿主
    • 37
    • 2
    小鼠
    克隆类型
    • 38
    • 1
    单克隆
    标记
    • 14
    • 6
    • 6
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    • 2
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    This C4BPA antibody is un-conjugated
    应用范围
    • 28
    • 22
    • 17
    • 13
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes complement component 4 binding protein (C4bp).
    产品特性
    Synonyms: C4BPA, C4BP, Proline-rich protein, PRP
    纯化方法
    Affinity Chromatography on Protein A.
    免疫原
    Native Human C4 binding protein. Genename: C4BP
    克隆位点
    10-07-14
    亚型
    IgG2b
    Top Product
    Discover our top product C4BPA Primary Antibody
  • 应用备注
    ELISA. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Borate buffered saline, pH 8.4 containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    C4BPA (Complement Component 4 Binding Protein, alpha (C4BPA))
    别名
    C4b-Binding Protein alpha (C4BPA 产品)
    别名
    CRES antibody, c4bp antibody, C4BP antibody, PRP antibody, complement component 4 binding protein, alpha chain antibody, C4b-binding protein alpha chain antibody, complement component 4 binding protein alpha antibody, complement component 4 binding protein, alpha antibody, LOC419851 antibody, c4bp antibody, C4BPA antibody, C4bpa antibody
    背景
    There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.Synonyms: C4BP, C4BPA, PRP, Proline-rich protein
    基因ID
    722
    UniProt
    P04003
    途径
    Complement System
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